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Toxic memories are those memories that trigger chemical responses in the brain that are deleterious to your health, both physically and mentally. They become like the ruts in your brain which prevent you from choosing any new course of action. These thoughts are transmitted in your brain by chemical packets (molecules of memory), which are laced with emotions. These emotions will overwhelm your reasoning and dictate your thoughts and responses making them out of proportion to the situation you are facing.
Learn the physiology of memory formation and how God designed our brains to be healed and how to overwrite negative thought patterns. You can "...be renewed in the spirit of your mind:... and ... put on the new man which was created according to God, in true righteousness and holiness". Eph 4:23,24 NKJV.